May 12, 2015

Liquid biopsies provide noninvasive care

Henry McKeand
Staff Writer

Liquid biopsies, a new type of blood test, could potentially provide a new noninvasive form of cancer care.  The biopsies look for and capture cancer cells found in the blood.  They utilize gene profiling to determine what mutations cause the cancer.  These biopsies are done as opposed to actually removing tissue from the tumor, and could potentially provide a more accurate way of discovering which cancer medicines will be most effective for an individual.  This could save health care costs by quickly finding the right drugs to use for treatment instead of having to experiment with different medicines. 


Liquid biopsies are usually done when it would be difficult to perform a tissue biopsy.  While they are fairly new and uncommon, some studies suggest that liquid biopsies could be equally or more effective than tissue biopsies.  Liquid biopsy research is still in its early stages, but it is already making progress.  Two years ago, it was rarely used for practical purposes, but now it is a more accepted form of care. 


Liquid biopsies are attractive to cancer patients who want to avoid as many invasive or surgical procedures as possible.  There is a clear desire for noninvasive cancer treatments, and other forms are currently being researched.  Trovagene, a company based in San Diego, is currently researching how to detect tumor DNA in urine.